Abstract
An integrated approach to guide the synthesis of reaction systems is presented, with the objective of identifying the best design while reducing development time. The approach is applicable to a variety of reaction systems including catalytic and non-catalytic single as well as multiphase reactions, polymerizations, and reactive extraction and crystallization. The systematic methodology integrates the Experiments, Synthesis, and Modeling activities into an efficient workflow. This minimizes wasted efforts in doing random experiments and modeling, while obtaining information necessary for a validated reactor design. The synthesis component assimilates the available information and drives all other activities. Required information flows between each of the components. Each iteration of the overall loop leads to greater certainty regarding the system behavior, and hence a tighter design for the reaction system. This methodology represents a new approach to the synthesis of reaction systems, and provides an efficient workflow to progress from a process demonstrated in the laboratory to a production reactor on the ground.
