Abstract
Crystallization is fast becoming the separation operation of choice in the pharmaceutical and specialty chemical industries. As a result, the problem of development of crystallization-based separations is becoming more and more important. Typically, this development problem consists of several experimental, synthesis, and modeling tasks that need to be performed in an evolutionary manner by a development team of chemical scientists and process engineers. Due to the complexity and magnitude of these tasks, software tools that provide quantitative results and qualitative insights to help the development team in handling them are extremely valuable. This is especially true in view of the ever-present time pressure and resource limitations. We have developed one such software tool called SLEEK ("Solid-Liquid Equilibrium Engineering Kit"). In this paper we will provide a glimpse into SLEEK and focus on demonstrating its use in handling various process development tasks.
