Abstract
Regeneration of synapses and restore of higher brain functions in CNS are reviewed including at molecular and cellular level. Two processes seems to be necessary to recover original functions after degeneration of CNS ; one is resynaptogenesis to make new neuronal networks which make it possible to get functional recovery ; another is, of course, learning by repetitive stimulation to repair original functions. The former process also may need long time and developments of new drugs which shorten this process are expected to facilitate rehabilitation of CNS.
