Distribution of the Ge Groups among the Thais

Abstract

The distribution of the Gc groups was investigated on 178 Thai adults, all of whom were in Central Chest Hospital, Bangkok, with tuberculosis. The phenotype frequencies were: Gc 1-1 66.85%, Gc 2-1 28.65% and Gc 2-2 4.49%. The goodness of fit was tested by the following equation: x²=n(c²-4bd)²/(2b+c)²(c+2d)² (d. f.=1) where, b, c and d meant the observed number of Gc 1-1, Gc 2-1 and Gc 2-2 respectively.
The results of test (x²=0.6917, 0.50>P>0.30) indicate that the distribution is in an agreement with HARDY-WEINBERG's law.
The gene frequencies calculated by maximum likelihood method were : Gc¹=0.8118±0.0207 and Gc²=0.1882±0.0207. The frequency of gene Gc¹ was higher than that of the Japanese (0.7730-0.7753; ISHIMOTO, 1963, OMOTO et al., 1964), Koreans (0.7586; OMOTO et al., 1964) or the Chinese (0.7693; CLEVE and BEARN 1961).