Clinical Application of Evoked Otoacoustic Emission for Diagnosis of Meniere's Disease

Abstract

The evoked otoacoustic emissions (EOAEs) were recorded from 55 patients, who had been clinically diagnosed as Meniere's disease before this study, in order to determine the usefulness of EOAEs for diagnosis of Meniere's disease. EOAEs were elicitted using Otodynamic Analyzer ILO88 before and after glycerol administration and the relationship between the change in hearing level and in parameters of EOAE (TEP, Repro) was investigated. The results were as follows: 1) Although there are several reports suggesting that EOAEs could not detect the change in hearing level at low frequency area less than 500Hz, we could detect the difference in EOAEs in such frequency area in Meniere's disease. 2) There was a statistically significant difference in EOAE parameters between before and 3 hours after glycerol administration. 3) The change in hearing level and EOAE parameters in each case was not always parallel after glycerol administration. From these rerults, we concluded that the detection rate of Meniere's disease could be improved by adding EOAEs as one of the parameters in Glycerol test.