Changes in NMDA Receptor Subunit mRNAs Distributed in The Rat Superior Olivary Complex

Abstract

The changes distribution NMDA receptor subunit mRNAs after Unilateral deafness was observed in the rat superior olivary complex (SOC) using in situ hybridization histochemistry. Silver grains density of NMDAR1 subunit mRNA was decreased in the lateral superior olive (LSO), medial superior olive (MSO) and lateral nucleus of the trapezoid body (LNTB). These changes were transient, and showed the peak after 5 days. No significant changes of NMDAR2 subunits was seen in all SOC unclei.