Biocontrol Science
Online ISSN : 1884-0205
Print ISSN : 1342-4815
ISSN-L : 1342-4815
Note
Stability of Weakly Acidic Hypochlorous Acid Solution with Microbicidal Activity
MASAYUKI ISHIHARAKAORU MURAKAMIKOICHI FUKUDASHINGO NAKAMURAMASAHIRO KUWABARAHIDEMI HATTORIMASANORI FUJITATOMOHARU KIYOSAWAHIDETAKA YOKOE
Author information
JOURNALS FREE ACCESS

2017 Volume 22 Issue 4 Pages 223-227

Details
Abstract

 Hypochlorous acid (HOCl) solution (200 ppm, pH 6) was prepared and evaluated for their stabilities and microbicidal activities. We demonstrated that HOCl is unstable against ultraviolet (UV) light, sunshine, contact with air, and elevated temperature (≧25℃). Furthermore, in the HOCl solution, the presence of excess NH2- or CHO-containing organic compounds such as proteins and carbohydrates, or of inorganic ions such as NO2-, SO3-, PO3-, Fe2+, Cu2+, and CuS, resulted in the rapid consumption of HOCl by oxidation reactions, and significantly decreased the microbicidal activity of the HOCl solution against coliform bacteria and total viable cell count. Thus, production of stable HOCl solution requires formulation in pure water harboring concentrations as low as possible of various compounds and ions, as well as storage in dark and cool conditions (<10℃) to maintain the concentration of HOCl molecules and microbicidal activity.

Information related to the author
© 2017 The Society for Antibacterial and Antifungal Agents, Japan
Previous article Next article
feedback
Top