Comparison of Various Disinfectants on Bactericidal Activity Under Organic Matter Contaminated Environments

YOKO SATO; MASAYUKI ISHIHARA; SHINGO NAKAMURA; KOICHI FUKUDA; MASAHIRO KUWABARA; TOMOHIRO TAKAYAMA; SUMIYO HIRUMA; KAORU MURAKAMI; MASANORI FUJITA; HIDETAKA YOKOE

doi:10.4265/bio.24.103

Note

Comparison of Various Disinfectants on Bactericidal Activity Under Organic Matter Contaminated Environments

YOKO SATO, MASAYUKI ISHIHARA, SHINGO NAKAMURA, KOICHI FUKUDA, MASAHIRO KUWABARA, TOMOHIRO TAKAYAMA, SUMIYO HIRUMA, KAORU MURAKAMI, MASANORI FUJITA, HIDETAKA YOKOE

Author information

YOKO SATO
Division of Biomedical Engineering, Research Institute, National Defense Medical College
MASAYUKI ISHIHARA
Division of Biomedical Engineering, Research Institute, National Defense Medical College
SHINGO NAKAMURA
Division of Biomedical Engineering, Research Institute, National Defense Medical College
KOICHI FUKUDA
Division of Biomedical Engineering, Research Institute, National Defense Medical College
MASAHIRO KUWABARA
Department of Plastic and Reconstructive Surgery, National Defense Medical College
TOMOHIRO TAKAYAMA
Department of Oral and Maxillofacial Surgery, National Defense Medical College
SUMIYO HIRUMA
Division of Biomedical Engineering, Research Institute, National Defense Medical College
KAORU MURAKAMI
Department of Oral and Maxillofacial Surgery, National Defense Medical College
MASANORI FUJITA
Division of Environmental Medicine, Research Institute, National Defense Medical College
HIDETAKA YOKOE
Department of Oral and Maxillofacial Surgery, National Defense Medical College

Keywords: Hypochlorous acid, Sodium hypochlorite, Bio-shell calcium oxides, Bactericidal activity, Disinfectant

JOURNAL FREE ACCESS

2019 Volume 24 Issue 2 Pages 103-108

DOI https://doi.org/10.4265/bio.24.103

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Abstract

The bactericidal activity of heated bio-shell calcium oxide (BiSCaO) powder suspension (pH 12.4) , hypochlorous acid (HClO; pH 6), sodium hypochlorite (NaClO; pH 8) , povidone-iodine (Isodine solution^®) , and chlorhexidine gluconate (Hibiscrub^®) under organic matter contaminated environments were compared for tests conducted on wood scraps and pig skin pieces that were incubated with normal bacterial flora (total viable counts and coliform bacteria) . The test results showed that BiSCaO suspension had higher bactericidal activity than HClO and NaClO. Furthermore, more than 10-fold higher concentrations of antiseptics such as povidone-iodine and chlorhexidine gluconate were required to achieve bactericidal activity comparable to that of BiSCaO suspension. Our results demonstrate the possibility of using BiSCaO suspension under organic matter contaminated environments as a disinfectant for environmental and food hygiene applications.

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