Histidinoalanine in Human Urine

Abstract

Histidinoalanine, a cross-linking component of connective tissue proteins, was detected in the acid hydrolysate of human urine. The concentrations in urines from newborn babies, children, and adults were 1.33±0.27, 0.77±0.23, and 0.89±0.33nmol/mg creatinine, respectively. Possible origins of urinary histidinoalanine are discussed.