Chromatin Remodeling and Transcription
Keywords:
chromatin remodeling,
histone acetylation,
histone deacetylation,
nucleosome,
transcrption
1998 Volume 124 Issue 6 Pages 1060-1064
Details
1998 Volume 124 Issue 6 Pages 1060-1064
The chromatin structure is essential not only for the compact packaging of the eukaryotic genome but also for regulation of transcription. This article provides an overview of chromatin modification upon transcriptional activation or repression, and chromatin remodeling. Interestingly, recent data demonstrate that chromatin remodeling in the promoter region is necessary for transcription.
