Abstract
Two hemichromes, obtained by addition of benzoate and sodium dodecvl sulfate, react with cyanide according to the following equations, respectively.
Based on these results, some discussions were made on the interrelation between the structural modifications of globin part and the affinity of globin-N group toward heme Fe.
The present investigation was supported by Prof. K. Kaziro, to whom the author's deep gratitude is due. I should like to express my thanks to Dr. G. Kikuchi for his helpful discussion during the course of this work. The author thanks also to the Ministry of Education for the Grant in Aid for Scientific Research. (K. Kaziro).