ENZYMATIC TRANSAMIDINATION FROM CANAVANINE TO GLYCINE BY HOG KIDNEY EXTRACTS
1956 Volume 43 Issue 5 Pages 675-681
Details
1956 Volume 43 Issue 5 Pages 675-681
An enzyme from hog kidney was found to catalyze the transfer of the amidine moiety of canavanine to glycine with the formation of glycocyamine. The enzyme was sensitive to heavy metal ions, and was inhibited by p-chloromercuribenzoate. No cofactor requirement was observed, and the optimal pH was about 7.4. It was suggested that an isothiourea-type enzyme-arnidine intermediate complex might be formed.
The author wishes to thank Dr. S. Sbibuy a and Dr. N. Izumiya for their valuable advice.
