1959 Volume 46 Issue 4 Pages 507-511
1. 3α, 7α, 12α, -Trihydroxy-24-methylcoprostanic acid was synthesized from norcholylmethyIketone and ethyl DL-α-bromopropionate by modified Reformatsky reaction.
2. Melting point of methyl 3α, 7α, 12α-trihydroxy-24-methylcoprostanate showed no depression, when mixed with methyl trihydroxyisosterocholanate derived from trihydroxyisosterocholenic acid (this acid was isolated from the bile of Bufo vulgaris formosus)
. The author wishes to thank Prof. T. Kazuno for valuable suggestions during the course of this work.