IMMUNOCHEMICAL STUDIES OF INSULIN

I. ENHANCEMENT OF NEUTRALIZING ANTIBODY FORMATION AGAINST INSULIN BY LIPOIDAL SUBSTANCES DERIVED FROM TUBERCLE BACILLI

Abstract

1. The antibodies responsible for insulin neutralization were induced in guinea pigs by injection of insulin in complete Freund's adjuvant.
2. The adjuvant effect of tubercle bacilli on production of neutralizing antibodies for insulin seems to depend mainly on Wax D fraction.