Abstract
1. The current work was carried out, using C14 glucose, to examine whether α-ketoglutaric acid, oxalacetic acid, and glyoxylic acid are synthesized from the glucose in the silkworm. Three kinds of keto acid were respectively isolated from the body fluid of silkworms which consumed C14 glucose as their 2, 4-dinitrophenylhydrazones, and their radioactivities were measured.
2. High radioactivity was recognized in α-ketoglutaric acid and in oxalacetic acid, but the radioactivity of glyoxylic acid was extremely low, showing that glucose is not a direct precursor for glyoxylic acid.
3. It seems to be doubtful that the formation of glyoxylic acid from glucose is the main pathway for glyoxylic acid synthesis.
