Fractionation and Characterization of Basic Proline-Rich Peptides of Human Parotid Saliva and the Amino Acid Sequence of Proline-Rich Peptide P-E

Abstract

Basic proline-rich peptides of human parotid saliva were fractionated and characterized. The amino acid sequence of one of the purified peptides, P-E, was determined to be SPPGKPQGP_??_PQGGNQPQG_??_PPPPGKPQG_??_PPQGGNRPQ_??_PPPPGKPQG_??_PPQGDKSRS_??_R.
The results demonstrate the repetitiveness of the partial sequence within the molecule and the occurrence of structures common to those of other salivary polypeptides such as P-C and Protein C.