Complete Amino Acid Sequence of a Basic Proline-Rich Peptide, P-D, from Human Parotid Saliva

Abstract

The complete amino acid sequence of a basic proline-rich peptide, P-D, isolated from human parotid saliva was determined to be Ser-Pro-Pro-Gly-Lys-Pro-Gln-Gly-Pro-Pro-Gln-Gln-Glu-Gly-Asn-Lys-Pro-GIn-GIy-Pro-Pro-Pro-Pro-Gly-Lys-Pro-Gln-Gly-Pro-Pro-Pro-Pro-GIy-Gly-Asn-Pro-GIn-GIn-Pro-GIn-AIa-Pro-Pro-Ala-GIy-Lys-Pro-GIn-Gly-Pro-Pro-Pro-Pro-Pro-GIn-GIy-GIy-Arg-Pro-Pro-Arg-Pro-AIa-GIn-Gly-Gln-GIn-Pro-Pro-Gln by conventional methods. P-D contains a number of repeating sequences and shows a high degree of homology with the salivary basic proline-rich peptides P-C and P-E.