BIOPHYSICS
Online ISSN : 1349-2942
ISSN-L : 1349-2942
Review Article
Role of TRP channels in the induction of heat shock proteins (Hsps) by heating skin
Wen-Li HsuTohru Yoshioka
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2015 Volume 11 Pages 25-32

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Abstract

Transient receptor potential (TRP) channels in skin are crucial for achieving temperature sensitivity to maintain internal temperature balance and thermal homeostasis, as well as to protect skin cells from environmental stresses such as infrared (IR) or near-infrared (NIR) radiation via heat shock protein (Hsp) production. However, the mechanisms by which IR and NIR activate TRP channels and produce Hsps intracellularly have been independently reported. In this review, we discuss the relationship between TRP channel activation and Hsp production, and introduce the roles of several skin TRP channels in the regulation of HSP production by IR and NIR exposure.

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© 2015 THE BIOPHYSICAL SOCIETY OF JAPAN
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