Abstract
For the purpose of clarifying the relationship between heat resistant Clostridium perfringens (welchii) in healthy peoples and the food poisoning due to this organism, the examination were carried out with healthy peoples living in Tokyo. 1. The mean value for carrier rate of heat-resistant Cl. perfringens in preschool children, primary school children and the adults was 14.7 per cent. There was no significant difference according to age, and at the same age level the carrier rate differed according to the group. 2. Seventy one (43.6%) of 163 strains of heat-resistant Cl. perfringens isolated from healthy people could be typed with Hobbs' typing sera. 3. The number of carrier in group might vary as much as 100% in a population (childrens and adults) living in the same environment, but no one strain predominated and no individual carried the same strain continuously. 4. The same type strains were isolated from a high percentage of patients with heat-resistant Cl. perfringens food poisoning, both in heated and unheated faecal specimens. But in healthy people, there was no relation in serological type between strains isolated directly and those isolated after boiling for 60 min. 5. Only a small percentage of strains isolated directly from healthy people were heat resistant, but over 50% of strains isolated directly from patients with food poisoning due to heat-resistant Cl. perfringens were heat resistant. In samples boiled for 60 min., on the other hand over the 80% of the strains isolated from both groups were heat resistant and there was no difference between the two. 6. The carrier rate of heat-resistant Cl. perfringens in patients with Dysentery and with Salmonella, pathogenic Escherichia coli, Staphylococcus aureus and Vibrio parahaemolyticus food poisoning were in the range of 5.7-29.7%. This carrier rate did not differ from that of healthy people. In particular, in cases of mass outbreak of food poisoning, no one serological strains of Cl. perfringens predominated.
https://ror.org/03ksn2k92 
