THE BULLETIN OF TOKYO MEDICAL AND DENTAL UNIVERSITY
Online ISSN : 2435-0761
Print ISSN : 0040-8921
IMMUNOCHEMICAL STUDIES ON BLOOD GROUP SPECIFICITY
II. INHIBITION OF HEMAGGLUTININ OF SOPHORA JAPONICA BY SIMPLE SUGARS.
Toshiaki OSAWAShichiro AKIYA
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JOURNAL OPEN ACCESS

1961 Volume 8 Issue 3.4 Pages 299-305

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Abstract
In 1951, Watkins and Morgan 1) described that not only hog and human H substances inhibit hemagglutination of O cells by eel anti-O (H) but also that simple sugars, for example, L-fucose and its structural homologues, would exert similar effect. It was for the first time that this fact had been presented as an example of the inhibition of normal antibody by simple sugars. Further, Morgan and Watkins 2) carried out an analogous study on the inhibition of hemagglutination of plant agglutinin by simple sugars. In the preceding paper of this series 3), partial purification of the agglutinin from Sophora japonica was reported and it was revealed that our partially purified product contained anti-B, anti-C and anti-O (H) ag­glutinins. This paper deals with the inhibition by simple sugars on hemagglutination of our partially purified agglutinin from Sophora japonica and the results obtained are discussed mainly from a standpoint of stereochemistry of sugar.
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© 1961 Tokyo Medical and Dental University (TMDU)
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