Determination of the content of bisphenol-A and its uncertainties by HPLC

Abstract

An accurate analysis of the amount of Bisphenol-A (BPA) in Polycarbonate (PC) was examined. BPA was extracted from PC under the Japanese food sanitation law (FSL). A new method was developed to determine the recovery under FSL by modifying the standard addition method. The recovery was determined to be 0.96 from this experiment. A comprehensive list of relevant sources of uncertainty under FSL operation was assembled. The uncertainty of the amount of BPA in PC was evaluated under the “guide to the expression of uncertainty in measurement (GUM)”. The amount of BPA in PC was evaluated: (38.89±1.59) μg/g (k = 2); here, k represents the coverage factor.