Calixarene Derivatives for Separation Analysis

Abstract

Macrocyclic ligands, calixarene derivatives have been preparaed as solvent extraction reagents. Based on the obtained data, four types of ion-exchange resins and an ion-selective electrode containing calix[4]arene derivatives have been prepared for applications to separation analysis. For resins containing calix[4]arene tetraacetic acid, the metal adsorption behavior was investigated by batchwise and column chromatographic methods. The resins containing calix[4]arene tetraacetic acid exhibited high lead selectivity. Methylene-crosslinked resin exhibited high lead capacity. Column chromatographic separation of lead and zinc ions by using the present resins was successfully achieved. An ion-selective electrode containing calix[4]arene tetraketone and tetra(2-pyridine) derivatives exhibited high silver selectivity. Calix[4]arene derivatives with high separation efficiency as solvent extraction reagents also exhibited a high efficiency when used as ion-exchange resins and ion-selective electrodes.