Abstract
Chloroform in pharmaceutical preparations was determined by the extraction method, and gas charomtography.
The sample solution containing 0.020.2 g of chloroform is extracted with 50 ml of toluene containing 0.2 % of n-heptane (internal standard). The chloroform solution obtained is centrifuged, and 1020 μl is injected, at a column temperature of 8090°C, into a gas chromatograph with a Silicone vacuum grease (25%)/Chromosorb P(6080 mesh) column.
The proposed method is more simple, and more rapid, and may be applied to the determination of a microquantity of chloroform when a small volume of solvent is used for extraction.
