1984 Volume 33 Issue 11 Pages T118-T121
The effective automatic stirring extractor presented previously for the rapid extraction of solid samples was applied to the assays of pharmaceutical tablets and vegetable drugs. The proposed extraction method was found to be superior to the methods authorized by JP X. In the assay of prednisolone tablets, the extraction chambers of 20 and 25 ml capacities were employed. The times taken to evacuate the chambers for 99.9 % were 20 and 25 min respectively. The results of the proposed method were the same as those of the authorized shaking extraction method. In the assay of capsicum extract, the results of extraction for 4 h were 16.39±0.21 % for the proposed method and 16.27±0.35 % for the authorized boiling extraction method with 95 % confidence limits. It was thus obvious that the application of the proposed method to those official methods simplified their extraction procedures by the elimination of the troublesome separation procedures required in those official methods. In the case of berberine extraction from coptis rhizome, the proposed method completed the extraction within only 2 h, whereas the authorized Soxhlet's method did not even in 24 h. The extraction flask with the calibration mark, with which the present extractor was equipped, was useful for dilution without transfer the extract to other volumetric flask.
