CATALASE DEPRESSING TISSUE FACTORS

TOXOHORMONE AND KOCHSAFT FACTOR

Abstract

In confirmation of Hargreaves and Deutsch, we found that tumor kocksaft factor clearly inhibits in vitro the activity of the solution of crystalline catalase, but it was also demonstrated that kocksaft prepared from normal liver, spleen, kidney, embryo, etc., brings about similar degree of inhibition. These facts, taken together with the inability of a potent toxohormone fraction to produce in vitro inhibition of crystalline catalase solution, seem conclusive in showing that the so-called kocksaftt factor is an entirely different entity from toxohormone.