ISOLATION OF THE MITOSIS PROMOTING SUBSTANCE, ONCOTREPHIN, FROM RAT ASCITES HEPATOMA (AH 130)

Abstract

Oncotrephin was isolated from experimental hepatoma (AH 130) of rat. It can be precipitated not only by 30-70% ethanol, but also by 50-70% saturated ammonium sulfate. The question of the identity of oncotrephin with the growthpromoting factors in the liver (Teir et al. Paschkis et al. and Martel et al.) was discussed.