Abstract
Intrahepatic topographical distribution of the protein-bound dye was investigated by autoradiography, using 14C-labeled 4-dimethylaminoazobenzene, in a precancerous liver of a rat which was induced by preliminary feeding of cold Butter Yellow. In the hepatic parenchyma, the highest number of 14C grains was observed in a region of benign nodular hyperplasia and a lesser number was found in atypical hyperplastic loci. The grains were almost negligible in both cholangiofibrosis and cystic region.
The significance of these findings and comparison with Weiler's findings or with results of our previous experiments are briefly discussed.
