INDUCTION OF HEPATOMA IN MICE BY BENZENE HEXACHLORIDE

Abstract

Among α-, β-, and γ-isomers of benzene hexachloride, both α- and γ-isomers induced a typical hepatoma, and none was found in mice fed the β-isomer. Hepatoma more often developed in male than in female mice. α-Fetoprotein was not detected in the serum of animals with hepatoma, by the Ouchterlony method.