CHANGE IN IMMUNOSENSITIVITY OF YOSHIDA SARCOMA PRODUCED BY CHEMICAL MODIFICATION OF CELL-SURFACE MEMBRANE

Takao IWAGUCHI; Toyoharu HOZUMI

doi:10.20772/cancersci1959.66.2_155

GANN Japanese Journal of Cancer Research

Print ISSN : 0016-450X

CHANGE IN IMMUNOSENSITIVITY OF YOSHIDA SARCOMA PRODUCED BY CHEMICAL MODIFICATION OF CELL-SURFACE MEMBRANE

Takao IWAGUCHI, Toyoharu HOZUMI

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Keywords: Chemical modification, Cell surface, Change in immunosensitivity, Yoshida sarcoma, Donryu rat

JOURNAL FREE ACCESS

1975 Volume 66 Issue 2 Pages 155-158

DOI https://doi.org/10.20772/cancersci1959.66.2_155

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Abstract

Change in immunosensitivity of various chemically modified cells to the specific antibody was investigated in the Donryu rat-Yoshida sarcoma system. Among various agents, Amphotericin-B and cetyltrimethylammonium bromide were effective in increasing the immunosensitivity. This effect was not due to the general damage of cell membrane but to the increase of antigen exposed on the cell-surface membrane.

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