POTASSIUM DICHROMATE-INDUCED CHROMOSOME ABERRATIONS AND ITS CONTROL WITH SODIUM SULFITE IN HAMSTER EMBRYONIC CELLS IN VITRO

Abstract

Addition of K₂Cr₂O₇ (0.1∼0.5μg/ml) to hamster embryonic cells for 24hr led to consistent chromosomal aberrations of cells including gaps, breaks, and exchange. The effect of K₂Cr₂O₇ was reduced by the addition of a reducing agent, Na₂SO₃.