ESTABLISHMENT OF A NEW HUMAN LYMPHOMA LINE THAT SECRETES PLASMINOGEN ACTIVATOR

Abstract

A new cell line, designated RC-K8, was established from the peritoneal effusion of a patient with histiocytic lymphoma. The RC-K8 had human male karyotype with 14q+ and was found to have B-cell (B1) and monocyte/macrophage (intracytoplasmic α subunit of S-100 protein) markers. A fibrin plate method demonstrated that RC-K8 cells release plasminogen activator in culture.