DETECTION OF 2-AMINO-3-METHYL-IMIDAZO[4, 5-f]QUINOLINE IN CIGARETTE SMOKE CONDENSATE

Mitsuko YAMASHITA; Keiji WAKABAYASHI; Minako NAGAO; Shigeaki SATO; Ziro YAMAIZUMI; Makoto TAKAHASHI; Naohide KINAE; Isao TOMITA; Takashi SUGIMURA

doi:10.20772/cancersci1985.77.5_419

Mitsuko YAMASHITA, Keiji WAKABAYASHI, Minako NAGAO, Shigeaki SATO, Ziro YAMAIZUMI, Makoto TAKAHASHI, Naohide KINAE, Isao TOMITA, Takashi SUGIMURA

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Keywords: 2-Amino-3-methylimidazo [4,5-f]quinoline, Cigarette smoke condensate, Blue cotton, Electrochemical detection

JOURNAL FREE ACCESS

1986 Volume 77 Issue 5 Pages 419-422

DOI https://doi.org/10.20772/cancersci1985.77.5_419

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Abstract

2-Amino-3-methylimidazo[4, 5-f]quinoline (IQ), which is mutagenic and carcinogenic, was found to be present in cigarette smoke condensate by liquid chromatography with an electrochemical detector and a photodiode-array detector. The amount of IQ was estimated to be 0.26ng per cigarette.

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