A Trial Study for Lens Capsule Regeneration Using iPS-derived Cell Aggregates

Abstract

Cell aggregation were differentiated from iPS cells derived from human iris by standstill and rotation culture method, made the section from cell block, and stained hematoxylin and eosin (H.E.) staining, immunostaining of αA-crystalline and p75NTR. Epithelial-like cells were arranged in a monolayer on the surface of the aggregate and strongly express αA-crystalline and p75NTR. Partially observed a part similar to the bow area at the late stage of lens development which is continuously multilayered inward, and a membrane-like structure.