Abstract
Exact mechanisms of early brain injury after subarachnoid hemorrhage (SAH) is still undetermined. We showed that reduction in oxidative stress may attenuate early brain injury after SAH via activation of Akt/GSK3β survival signaling in rat SAH model. We also showed that diffusion weighted imaging (DWI) is useful tool to detect early brain injury after SAH in the clinical setting. DWI can provide an objective means to estimate the outcome of poor-grade SAH. These research about early brain injury after SAH could provide new therapeutic approach.
