2018 Volume 30 Issue 1 Pages 29-33
Evolution of reperfusion therapy in acute stroke has been accelerated after the encouraging evidence of endovascular therapy after/without iv rt-PA. Reperfusion therapy has moved from time window selection to tissue window selection, although certain imaging criteria has not yet been established. Penumbral imaging has the potential to solve this tissue selection issue both by CT and MRI scanning. Optimal mismatch ratio between MRI DWI/CT perfusion and PWI Tmax may predict the favorable outcome. These criteria must be discussed to improve the reperfusion therapy strategy in further perspectives using multimodality imaging along with expanding the treatment time window.
