Abstract
A high performance system for the molecular dynamics simulation of biological molecules was constructed by combining a software package, Peach, with a special-purpose computer, Grape. The resultant simulator "Peach-Grape system" was used to analyze several important biological molecules including the Hin/DNA complex, the trp-Repressor/DNA complex, and Calmodulin. In addition to those simulations performed by the Peach-Grape system, other simulation studies of biomolecules by special-purpose computers are briefly reviewed.
