Oral Appliance Therapy improved Frequent Ventricular Premature Complexes during Sleeping in a Patient with Obstructive Sleep Apnea Syndrome.

Abstract

This is a report of a 47-yo female patient who had been suffering from obstructive sleep apnea(OSAS) concomitant with frequent ventricular premature complexes(VPCs) during sleeping which might lead to sudden death. Standard polysomnography(PSG) revealed her OSAS with apnea-hypopnea index(AHI) of 14.7, the longest apnea time(LAT) of 83.5 sec, nadir SpO₂ of 81%, and snoring index(SI) of 295.1. Frequent VPCs(total of 763 times) were also observed during the PSG. Oral appliance(ORAP) therapy was applied to her OSAS because she could not tolerate nasal continuous positive airway pressure previously applied elsewhere. The PSG under ORAP therapy showed the improvements of OSAS(AHI of 0.6, LAT of 22.3sec, nadir SpO₂ of 93%, SI of 0.1) as well as the disappearance of frequent VPCs.