Abstract
Introduction: Modified ultrafiltration(MUF) can remove excess water and inflammatory mediators from the circulation after cardiopulmonary bypass(CPB) in pediatric patients. However, the value of MUF in adult patients remains unknown.
Methods: We retrospectively investigated hemodynamic functions after MUF in 70 adult patients who had undergone cardiovascular surgery.
Results: Systolic blood pressure was significantly increased after MUF. The hematocrit after CPB decreased in the control, but not in the MUF group. The MUF group required less red blood cell products, colloids and crystalloid solution resuscitation than the control group. No adverse events were associated with MUF.
Discussion: Modified ultrafiltration can safely achieve hemoconcentration, resulting in increases of systolic blood pressure after CPB, less intraoperative red blood cell transfusion and lower postoperative fluid resuscitation.
Conclusion: Modified ultrafiltration can improve hemodynamic function and diminish transfusion requirements not only for pediatric, but also for adult patients.
