2005 Volume 1 Issue 3 Pages 311-321
The Sasaki Foundation was established as a nonprofit research foundation in 1939 by Dr. Takaoki Sasaki. The Sasaki Foundation has been formed by two organizations: institute (the Sasaki Institute) and hospital (the Kyoundo Hospital). Until now, many excellent basic studies in the medical field, especially regarding cancer research, have been conducted in the Sasaki Institute. At a period of 1920s, Dr. Sasaki already proposed a new scientific field, namely "chemical pathology", this concept corresponding to today's "toxicologic pathology", and among studies conducted under the concept, the most remarkable and epoch-making study is "the induction of hepatic cancer in rats by o-aminoazotoluole, one of azo dyes" by Drs. Sasaki (First Director of the Sasaki Institute) and Tomizo Yoshida (2nd Director). Since then, in the institute (especially Department of Pathology), numerous studies concerning risk assessment of chemicals have been conducted from the standpoint of toxicity/carcinogenicity.
