2006 Volume 2 Issue 1 Pages 104-134
Organisation for Economic Co-operation and Development (OECD) member countries decided to undertake the investigation of high production volume chemicals (HPV) in 1990, and the OECD HPV programme has been performed for an initial assessment to physical/chemical properties, exposure, ecotoxicity and human health since 1992. The summary records of the 19th and 20th SIDS (Screening Information Data Set) Initial Assessment Meetings (SIAMs) were previously reported. This paper introduces progress of the OECD HPV programme from the 1st to 18th SIAM. The initial assessment documents for a total of 445 substances were agreed through the 1st to18th SIAMs, and 99 documents were submitted by Japanese government. Among them, 42 documents were prepared with the International Council of Chemical Associations (ICCA), and all the documents that Japanese government submitted were agreed at the previous SIAMs.