1975 Volume 23 Issue 8 Pages 2546-2551
Thirty-two patients with acute genitourinary tract infections were treated with oral administration of 0. 5 g cephradine t. i. d. for 7 days and the following results were obtained.
1. Drug sensitivity of E. coli clinically obtained to cephradine was comparable with that to CEX.
2. On termination of the treatment, the symptoms were disappeared in 27 cases and pathogens were eliminated in 29 cases, respectively.
3. Among 32 patients, clinical cure was obtained in 23 on the 4 th day after start of the treatment and 29 on the 8 th day, respectively.
4. Reccurrence was noted in 4 cases out of 31 on whom follow up studies were complete.
5. With an exception of a case with allergic rash, no adverse effect on renal function, liver function and peripheral blood findings and also no gastrointestinal disturbances were observed.