CHEMOTHERAPY
Online ISSN : 1884-5894
Print ISSN : 0009-3165
ISSN-L : 0009-3165
CLINICAL EXPERIENCES OF PIVMECILLINAM ON URINARY TRACT INFECTIONS
NOBUO FUJIMURATOKUZO FUKUKAWAKAZUO KUROKAWA
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1977 Volume 25 Issue 1 Pages 298-304

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Abstract

Thirty-nine in-and out-patients suffering from urinary tract infections were treated with pivmecillinam.
Pivmecillinam was administered orally at the dosage of 300 mg or900 mg for 7 days.
Of 26 patients with simple acute and chronic cystitis, clinical responses were excellent in 20, good in 3 and poor in 3.
Of 13 patients with complicated chronic cystitis, excellent in 5, good in one, fair in 3 and poor in 4.
Efficacy rates were 74.4% of patients with cystitis, 88.5% of 26 patients with simple cystitis and 46.2% of 13 patients with complicated cystitis.
Out of 39 strains, 30 strains (76.9%) were disappeared, 7 strains (18.0%) were unchanged and 2 strain (5.1%) were substituted.
As for side effect, anorexia was observed in 3 patients (7.7%).
Value of S-GOT and S-GPT were in normal range after treatment inall cases.

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© Japanese Society of Chemotherapy
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