1977 Volume 25 Issue 1 Pages 298-304
Thirty-nine in-and out-patients suffering from urinary tract infections were treated with pivmecillinam.
Pivmecillinam was administered orally at the dosage of 300 mg or900 mg for 7 days.
Of 26 patients with simple acute and chronic cystitis, clinical responses were excellent in 20, good in 3 and poor in 3.
Of 13 patients with complicated chronic cystitis, excellent in 5, good in one, fair in 3 and poor in 4.
Efficacy rates were 74.4% of patients with cystitis, 88.5% of 26 patients with simple cystitis and 46.2% of 13 patients with complicated cystitis.
Out of 39 strains, 30 strains (76.9%) were disappeared, 7 strains (18.0%) were unchanged and 2 strain (5.1%) were substituted.
As for side effect, anorexia was observed in 3 patients (7.7%).
Value of S-GOT and S-GPT were in normal range after treatment inall cases.