DRUG SUSCEPTIBILITY OF SERRATIA MARCESCENS

COMPARISON OF THE STRAINS CLINICALLY ISOLATED IN 1973 AND THOSE ISOLATED FROM URINARY TRACT INFECTION IN 1975

Abstract

The susceptibility of Serratia marcescens isolated in 1973 and that isolated from urinary tract infection in 1975, was determined against each of 20 antimicrobial agents, and the following results were obtained.
1. Serratia marcescens isolated from urinary tract infection in 1975 was resistant to many antimicrobial agents compared with the strains in 1973.
2. Generally, the majority of Serratia marcescens was susceptible to amikacin, gentamicin and KW-1062, while 35 percent of the strains in 1975 was multiple resistant to gentamicin, KW-1062, dibekacin and tobramycin.
3. Almost all strains of Serratia marcescens were resistant to β-lactam antibiotics, while penicillins were slightly more active than cephalosporins.
4. The susceptibility to antimicrobial agents was different between pigmented strains and nonpigmented strains.