COMPARATIVE DOUBLE BLIND TRIAL OF CEFATRIZINE AND CEPHALEXIN IN THE TREATMENT OF COMPLICATED URINARY TRACT INFECTION
1978 Volume 26 Issue 1 Pages 1-9
Details
1978 Volume 26 Issue 1 Pages 1-9
Comparative double blind trial of cefatrizine (CFT) and cephalexin (CEX) was performed with 197 patients of complicated urinary tract infection. Patients were treated for a week at a daily dose of 1 g (A group) or 2 g (B group) of CFT or 2 g of CEX (C group).
The results obtained were summarized as follows ;
The background characteristics of the three groups were statistically analyzed and no significant difference was found.
The clinical response was evaluated on 70 cases of 1 g CFT, on 66 cases of 2 g CFT and on 61 cases of 2g CEX. The clinical response rate was 70. 0% with A group, 71. 2% with B group and 78.7% with C group, showing no sighificant difference.
Side effects were observed in 4. 9% of 82 cases with A group, in 1. 2% of 82 cases with B group and in 1. 3% of 75 cases with C group, showing no significant difference.
Recurrence within a week after completion of the treatment was observed in 27. 9% of 43 cases with A group, in 30. 2% of 43 cases with B group and 26. 7% of 45 cases with C group, showing no significant difference.
And these results demonstrated that the treatment either at a daily dose of 1 g or 2g of CFT or 2g of CEX was effective in the field of the complicated urinary tract infection.
