STUDIES ON INTRATISSULAR CONCENTRATION OF ANTIBIOTICS IN ORAL SURGERY

Abstract

The gingival tissues concentration of cephaloridine in oral surgical field have been analysed with 120 cases, and the following results were obtained.
CER was injected intramuscularly to man to investigate the concentration of its serum and gingival tissue. Maximum serum and gingival tissue levels were attained from 30 to 60 minutes after administration.
CER concentration in normal tissues was generally somewhat higher than scar tissues.
There was no difference on the CER concentration among the methods of anesthesia.
The sexual difference of CER concentration was not shown.