Abstract
1) PC-904 was administered into 8 respiratory tract. infections caused by either K. aerogenes or D. pneumoniae or Ps. aeruginosa or A. xylosoxidans, and clinical improvements were observed in 5 of them. It is noteworthy that PC-904 was effective excellently against K. aerogenes-induced pneumonia.
2) The best method of administration and dosage of PC-904 was i. v. drip-infusion of 2g twice a day, but usually 1 g twice a day was enough for common acute pneumonia.
3) As far as the side effects were concerned, 1 pyrexia, 1 dyspnea attack, 3 elevations of serum GOT and 2 elevations of BUN were observed, but all these symptoms were improved after the withdrawal of the drug.
