FUNDAMENTAL AND CLINICAL STUDIES ON AB-206 IN THE URINARY TRACT INFECTIONS
1978 Volume 26 Issue Supplement4 Pages 155-160
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1978 Volume 26 Issue Supplement4 Pages 155-160
AB-206, a new chemotherapeutic agent, was studied both fundamentally and clinically. Results were summarized as follows.
1. MICs of AB-206 for 12 standard strains, 50 urinary E. coli and 25 urinary P. aeruginosa were superior to those of NA.
2. In 27 cases of urinary tract infections, AB-206 was administered at a daily dose of 1g. Satisfactory results were obtained in 15 cases ; 70% in 10 cases of acute simple cystitis, 53% in 15 cases of chronic complicated urinary tract infections. Two cases were dropped out.
3. Side effects were observed in 4 of total 27 cases (nausea, loss of appetite, diarrhea and dizziness). Transient increase of s-GOT was observed in one case.
