1980 Volume 28 Issue Supplement6 Pages 569-574
Cefoperazone (CPZ, T-1551), a new cephalosporin antibiotic, was studied fundamentally and clinically, and the following results were obtained.
CPZ was compared with cefazolin and piperacillin in antibacterial activity against gram-negative bacilli and gram-positive cocci isolated from clinical materials. Against gram-negative bacilli CPZ was the most active than cefazolin. Against Pseudomonas and S. marcescens CPZ showed equal activity to piperacillin.
As the result of CPZ treatment, CPZ was effective in all 11 cases (8 with respiratory tract infection, 1 with biliary tract infection and 2 with urinary tract infection).
No side effects were observed with CPZ in hemogram, liver function, kidney functinn and others.
