Netilmicinの臨床的研究

河合 美枝子; 神崎 令子; 安達 正則; 相馬 隆; 今高 国夫; 中野 昌人; 滝塚 久志; 岡山 謙一; 勝 正孝; 新井 俊; 青柳 昭雄; 高波 巌

doi:10.11250/chemotherapy1953.29.Supplement3_127

CLINICAL STUDY WITH NETILMICIN

MIEKO KAWAI, REIKO KANZAKI, MASANORI ADACHI, TAKASHI SOHMA, KUNIO IMATAKA, MASATO NAKANO, HISASHI TAKIZUKA, KENICHI OKAYAMA, MASATAKA KATSU, SHUN ARAI, AKIO AOYAGI, IWAO TAKANAMI

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1981 Volume 29 Issue Supplement3 Pages 127-134

DOI https://doi.org/10.11250/chemotherapy1953.29.Supplement3_127

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Abstract

Netilmicin was given to 20 patients, 13 with respiratory tract infections and 7 with urinary tract infections. The drug was administered intramuscularly at a daily dose of 150mg or 200mg.
1) Efficacy rate was counted 61% in respiratory tract infections and 71% in UTI. The overall efficacy was 65%.
2) Netilmicin was especially effective to infections by E. coli and Klebsiella and not so effective to infections by P. aeruginosa.
3) Transient elevation of transaminases was noted in one case. Nephrotoxicity and ototoxicity were not noted.

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