Abstract
To evaluate the clinical efficacy of cefotetan (CTT, YM09330), the treatment was made with the drug in 62 patients including 32 with pneumonia, 4 with acute bronchitis, 2 with chronic bronchitis, 1 with purulent tonsillitis, 4 with acute pyelonephritis, 1 with chronic pyelonephritis, 7 with acute cystitis, 10 with chronic cystitis and 1 with acute cholecystitis. Response was excellent in 20 patients, good in 36, fair in 1 and poor in 5.
Side effect noted was fever in 1 patient. Laboratory abnormalities were observed as luekopenia in 3 and thrombocytopenia in 2 patients. Slight elevations of GOT and Al-P were observed each 1 patient.
From the above results, the drug can be considered to be useful against respiratory tract infections and urinary tract infections.
